VirScan® - Viral PhIP-Seq Antibody Profiling Services

Most Vertebrate Viral Proteomes in a Single Assay

Most viral proteomes epitope-level autoantibody profiling service via T7 phage display and immunoprecipitation sequencing (PhIP-Seq).

VIRSCAN PHIP-SEQ

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HuScan® Human Proteome Phage-display (PhIP-Seq)

Detects Antibodies Against 48,921 Unique Human Proteins

HuScan® PhIP-Seq is composed of an entire normal human proteome as defined by the NCBI RefSeq database.

HUSCAN PHIP-SEQ

MouseScan® Murine Proteome Phage-display (PhIP-Seq)

Detects Antibodies Against 50,135 Unique Murine Proteins

Murine proteome epitope-level autoantibody profiling services via T7 phage display and immunoprecipitation sequencing (PhIP Seq).

MOUSESCAN PHIP-SEQ

CDI LABS NEWS |

Jul 9, 2024Press Release: CDI Labs Launches New VirScan, HuScan, and MouseScan Services for Massively Multiplexed Anal...

Feb 4, 2020Press Release: CDI Labs Launches Two New Powerful Assays to its Biomarker Discovery Platform

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The World's Most Comprehensive Portfolio for Autoantibody Detection

Transformational products and services for proteome-wide autoantibody profiling, biomarker discovery, cross-reactivity screening, and other whole-proteome target identification and interaction assays

We Offer the Most Powerful Antigen Libraries

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Most Vertebrate Viral Proteomes

Detects antibodies against 68,000+ vertebrate viral protein sequences

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All Human Proteome

Detects antibodies against 48,921 unique human proteins and protein isoforms

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All Murine Proteome

Detects antibodies against 50,135 unique murine proteins and protein isoforms

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21,000+ Full-length Proteins

GST-purified and validated recombinant proteins and isoform variants

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Cell Membrane-embedded

Purified virion display correctly-folded membrane-embedded GPCRs

HuProt and VirD are provided by CDI Labs USA.

CDI Labs Autoantibody Seromics

The serome is the total secreted antibody repertoire of a single individual; each serome is unique and created by a person's lifetime of adaptive immune experiences. The goal of the emerging scientific field of 'autoantibody seromics' is to understand the largest impacts of the serome on human health, disease, and clinical outcomes.

More Content and Better Data

We start with sequence-confirmed plasmids, then individually express and GST-purify proteins from S. cerevisiae. Piezolelectric printing is used to spot these in duplicate alongside controls. Quality is confirmed with anti-GST QA/QC. Successful folding demonstrated by kinase autophosphorylation assay.

PUBLICATIONS

220+peer-reviewed publications

With over 220 publications (and growing), our antibody seromics solutions and HuProt array continue to play a key role in life sciences by contributing to critical studies that help accelerate research, advance discoveries, and translate discoveries to novel products that improve human health.

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CUSTOMER-BASE

190+customer base

Our customer base continues to expand throughout North America, Europe, and Asia Pacific, and is a testament to the quality and consistency of our products and services.

FOUNDERS

Boeke, Zhu & Blackshawat Johns Hopkins University

Funded by NIH Common Fund Support for the Development of Protein Capture Reagents and Technologies, the HuProt Protein Microarray was created by CDI Labs co-founders Jef Boeke, Heng Zhu, Dan Eichinger, and Seth Blackshaw, faculty members at the High Throughput Biology (HIT) Center at the Johns Hopkins University School of Medicine.

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Data and technology validated by scientists

"This (VirScan) assay, which uses phage display immunoprecipitation and sequencing, is a sensitive and focused high-comprehensive approach that enables thorough serological profiling of antiviral antibodies in humans and, consequently, the identification of viral exposure throughout the human virome."

Faculty of MedicineResearch Institution (as mentioned in "Human virome profiling identified CMV as the major viral driver of a high accumulation of senescent CD8+ T cells in patients with advanced NSCLC" - Science Advances - November 2023)

Data and technology validated by scientists

"We elected to use the HuProt Microarray because it is an extensive platform that contains over 21,000 unique, individually purified full-length human proteins and protein isoforms in duplicate, covering more than 81% of the proteome."

OncologistSchool of Medicine Research (as mentioned in "Baseline Serum Autoantibody Signatures Predict Recurrence and Toxicity in Melanoma Patients Receiving Adjuvant Immune Checkpoint Blockade" - AACR Clinical Caner Research - September 2022)

Data and technology validated by scientists

"By using (HuProt) protein arrays, we were able to evaluate a broader range of antigens compared to previous investigations."

Senior ScientistBiotech Research (poster presentation at the San Antonio Breast Cancer Symposium 2023)

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HuProt™ Proteome Microarray

VirScan™ PhIP-Seq*

HuScan® PhIP-Seq*

MouseScan™ PhIP-Seq*

VirD™ Membrane Arrays

Antibody Development & Manufacturing

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* This service is provided exclusively by CDI Labs Canada.

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